Berberine chloride (Natural Yellow 18) is an alkaloid derived from Hydrastis canadensis L. of the Berberidaceae family, serving as a commonly used intestinal antibacterial agent. Berberine chloride exhibits biological activities including anti-inflammatory, hypoglycemic, lipid-regulating, antitumor, and cardiovascular protective effects. Berberine chloride can be utilized in research on chronic diseases and tumors.