Lenvatinib (E7080) is a multi-target receptor tyrosine kinase inhibitor that inhibits VEGFR1-3, FGFR1-4, KIT, PDGFR, and RET, and has oral activity. Lenvatinib has the strongest inhibitory activity on VEGFR2 and VEGFR3 (IC50=4/5.2 nM). Lenvatinib has strong anti-tumor activity.
Molecular Weight:
426.85
Purity:
0.9996
CAS Number:
[417716-92-8]
Formula:
C21H19ClN4O4
Target:
PDGFR|||VEGFR|||c-RET|||FGFR|||c-Kit
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