Niclosamide is a classic salicylanilide antiparasitic drug and a multi-target, low-toxicity, broad-spectrum small-molecule modulator with anthelmintic and antitumor activity. Niclosamide disrupts the parasites energy metabolism by uncoupling mitochondrial oxidative phosphorylation, leading to reduced ATP production and ultimately killing the parasite. Niclosamide is a STAT3 inhibitor with an IC50 of 0.25 µM in HeLa cells.
Molecular Weight:
327.12
Purity:
96.83%
CAS Number:
[50-65-7]
Formula:
C13H8Cl2N2O4
Target:
Antibiotic|||Parasite|||STAT
T0711
* VAT and and shipping costs not included. Errors and price changes excepted
