Acetohexamide (Acetohexamid) is an intermediate-acting, first-generation sulfonylurea with hypoglycemic activity. It inhibits sulfonylurea receptor 1 (SUR1) linked to the inwardly rectifying potassium channel (KIR6.2) with Ki values of 22.9 and 14.2 µM in HEK293 cells transfected with the human receptor and in rat brain, respectively. Acetohexamide is metabolized in the liver to its active metabolite hydroxyhexamide.
Molecular Weight:
324.4
Purity:
99.01%
CAS Number:
[968-81-0]
Formula:
C15H20N2O4S
Target:
Potassium Channel|||NADPH|||Others
T0816
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