Tinidazole (CP12574)a is a 5-nitroimidazole derivative with the antiprotozoal property. Although the mechanism of action has not been fully elucidated, it has been suggested that tinidazole is metabolized and yields nitrite anions and metronidazole. Metronidazoles nitro group, in turn, is reduced via the parasite ferredoxin, thereby generating a series of free nitro radicals including nitro anions. Toxicity is achieved via depletion of sulfhydryl groups and DNA strand breaks with multiple hits having an additive effect and ultimately leading to cell death.
Molecular Weight:
247.27
Purity:
99.91%
CAS Number:
[19387-91-8]
Formula:
C8H13N3O4S
Target:
Antibiotic|||Antibacterial|||Parasite
T0893
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