Cyclosporin A is a natural product and an active fungal metabolite, classified as a cyclic polypeptide immunosuppressant. It binds to cyclophilin and inhibits the activity of calcineurin (IC50 = 7 nM) as well as CD11a/CD18 adhesion molecules. It is commonly used to induce uremia models.
Molecular Weight:
1202.61
Purity:
98.00%
CAS Number:
[59865-13-3]
Formula:
C62H111N11O12
Target:
Complement System|||Antibiotic|||Phosphatase
T0945
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