7-Chlorokynurenic acid (7-chloro-4-hydroxy-2-carboxyquinoline) is an effecitve and selective antagonist of NMDA receptor with IC50 of 0.56 µM for the glycine B coagonist site. 7-Chlorokynurenic acid inhibits the reuptake of glutamate into synaptic vesicles with a Ki of 0.59 µM and shows antinociceptive actions after neuraxial delivery.
Molecular Weight:
223.61
Purity:
98.83%
CAS Number:
[18000-24-3]
Formula:
C10H6ClNO3
Target:
GluR|||NMDAR|||iGluR
T10191L
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