APX-115 free base (Ewha-18278 free base) is a potent, orally active pan NADPH oxidase (Nox) inhibitor with inhibition constants (Kis) of 1.08 µM, 0.57 µM, and 0.63 µM for Nox1, Nox2, and Nox4, respectively, and it effectively prevents kidney injury.
Molecular Weight:
279.34
Purity:
98.39%
CAS Number:
[1270084-92-8]
Formula:
C17H17N3O
Target:
NADPH-oxidase|||NADPH
T10353
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