CSN5i-3 is a potent, selective, and orally available inhibitor of the proteolytic subunit of the CSN complex, CSN5. It inhibits CSN-catalyzed Cul1 deneddylation with an IC50 value of 5.8 nM. CSN5i-3 has a killing effect on a variety of cancer cells and can be used as an anticancer drug. [2]
Molecular Weight:
505.56
Purity:
>99.99%
CAS Number:
[2375740-98-8]
Formula:
C28H29F2N5O2
Target:
Apoptosis|||Others
T10895
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