DBPR112 is an orally active furanopyrimidine-based EGFR inhibitor with IC50s of 15 nM for EGFRWT and 48 nM for EGFRL858R/T790M, capable of occupying the ATP-binding site and demonstrating significant antitumor efficacy.
Molecular Weight:
533.62
Purity:
0.9925
CAS Number:
[1226549-49-0]
Formula:
C32H31N5O3
Target:
EGFR
T10965
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