The cytotoxicity of DC0-NH2 is 1000 times that of commonly used anti-cancer drugs (such as doxorubicin). It is the effect part of ADC. It is a simplified simulation of DC1 and has better stability. DC0-NH2 can bind to the small groove of DNA, and then adenine residue is alkylated by its propabenzindole (CBI) component.
Molecular Weight:
550.01
CAS Number:
[615538-51-7]
Formula:
C31H24ClN5O3
Target:
ADC Cytotoxin
T10968
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