FM26 has a distinct isoxazole chemotype and effectively reduces IL-17a mRNA production in EL4 cells. FM26 is a potent and allosteric retinoic acid receptor-related orphan receptor gammat (RORgammat) inverse agonists with an IC50 of 264 nM.
Molecular Weight:
461.82
CAS Number:
[2407981-35-3]
Formula:
C22H15ClF3N3O3
Target:
ROR
T11308
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