FTI-2148 diTFA, a dual inhibitor targeting both farnesyl transferase (FT-1) and geranylgeranyl transferase-1 (GGT-1), functions as a RAS C-terminal mimetic. It exhibits potent inhibitory capabilities with IC50 values of 1.4 nM for FT-1 and 1.7 µM for GGT-1, respectively.
Molecular Weight:
566.6
CAS Number:
[817586-01-9]
Formula:
C26H29F3N4O5S
Target:
Others|||Transferase
T11330
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