GB-110 selectively induces PAR2-mediated intracellular Ca2+ release in HT29 cells with an EC50 of 0.28 µM. GB-110 is a potent, orally active, and nonpeptidic protease activated receptor 2 (PAR2) agonist.
Molecular Weight:
608.77
CAS Number:
[1252806-70-4]
Formula:
C33H48N6O5
Target:
Protease-activated Receptor|||Others
T11369
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