GNF362 is an orally available, selective and potent inhibitor of inositol trisphosphate 3kinase B (ITPKB), inhibits Itpka and Itpkc, overcomes TMZ chemoresistance, and selectively deletes donor allogeneic reactive T-cells.GNF362 reverses the migratory stimulatory effects of ITPKA overexpression.
Molecular Weight:
426.44
Purity:
99.63%
CAS Number:
[1003019-41-7]
Formula:
C22H21F3N6
Target:
Phosphatase
T11446
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