GSK2245035 is a highly selective intranasal TLR7 agonist with preferential Type-1 interferon (IFN)-stimulating properties (pEC50s: 9.3 and 6.5 for IFNalpha and TFNalpha). It effectively suppresses allergen-induced Th2 cytokine production in human peripheral blood cell cultures.
Molecular Weight:
390.52
CAS Number:
[1207629-49-9]
Formula:
C20H34N6O2
Target:
Others|||TNF|||IFNAR|||TLR
T11482
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