GSK2945 is a highly specific Rev-erbalpha/REV-ERBalpha (mouse/human reverse erythroblastosis virus alpha) antagonist (EC50s: 21.5 µM and 20.8 µM). It enhances cholesterol 7alpha-hydroxylase (CYP7A1) level and cholesterol metabolism.
Molecular Weight:
421.34
CAS Number:
[1438071-12-5]
Formula:
C20H18Cl2N2O2S
Target:
Cytochromes P450|||Others
T11490
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