GSK2945 hydrochloride is a highly specific Rev-erbalpha/REV-ERBalpha (mouse/human reverse erythroblastosis virus alpha) antagonist (EC50s: 21.5 µM and 20.8 µM). It enhances cholesterol 7alpha-hydroxylase (CYP7A1) level and cholesterol metabolism.
Molecular Weight:
457.8
Formula:
C20H19Cl3N2O2S
Target:
Others
T11490L
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