HPN-01 (IKK inhibitor XII) is a selective IKK inhibitor that inhibits IKK-alpha, IKK-beta, and IKK-epsilon. HPN-01 reduces the severity of the disease, attenuates the immune imbalance, and prolongs the lifespan of mice in a model of autoimmune encephalomyelitis, and can be used to study immune disorders.
Molecular Weight:
401.87
Purity:
98.17%
CAS Number:
[928655-63-4]
Formula:
C19H16ClN3O3S
Target:
IkappaB/IKK
T11573
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