iFSP1, a potent, selective, and glutathione-independent ferroptosis suppressor protein 1 (FSP1) (AIFM2) inhibitor with an EC50 of 103 nM, sensitizes diverse human cancer cell lines to ferroptosis inducers like (1S,3R)-RSL3. It uniquely triggers ferroptosis in GPX4-knockout cells overexpressing FSP1.
Molecular Weight:
323.35
Purity:
0.9974
CAS Number:
[150651-39-1]
Formula:
C20H13N5
Target:
Ferroptosis
T11631
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