J-113863, CAS [[353791-85-2]]

Catalog Number: TGM-T11699
Article Name: J-113863, CAS [[353791-85-2]]
Biozol Catalog Number: TGM-T11699
Supplier Catalog Number: T11699
Alternative Catalog Number: TGM-T11699-1MLX10MM(INDMSO),TGM-T11699-1MG,TGM-T11699-2MG,TGM-T11699-5MG,TGM-T11699-10MG,TGM-T11699-25MG,TGM-T11699-50MG,TGM-T11699-100MG
Manufacturer: TargetMol
Category: Biochemikalien
J-113863 is also a potent antagonist of the human CCR3 (IC50 of 0.58 nM) , but a weak antagonist of the mouse CCR3 (IC50 of 460 nM). J-113863 is inactive against CCR2, CCR4 and CCR5, as well as the LTB4 or TNF-alpha receptors. Anti-inflammatory effect. J-113863 is a potent and selective CCR1 (CD18) antagonist with IC50 values of 0.9 nM and 5.8 nM for human and mouse CCR1 receptors, respectively.
Molecular Weight: 655.44
Purity: 95.11%
CAS Number: [353791-85-2]
Formula: C30H37Cl2IN2O2
Target: CCR
T11699