JBJ-04-125-02 can inhibit cancer cell proliferation and EGFRL858R/T790M/C797S signaling. JBJ-04-125-02 has anti-tumor activities. JBJ-04-125-02 is a potent, mutant-selective, allosteric and orally active EGFR inhibitor with an IC50 of 0.26 nM for EGFRL858R/T790M.
Molecular Weight:
543.61
CAS Number:
[2060610-53-7]
Formula:
C29H26FN5O3S
Target:
JAK|||EGFR
T11714
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