KY-05009 is a chemical compound that effectively suppresses TGF-beta1-induced epithelial-to-mesenchymal transition (EMT) in human lung adenocarcinoma cells, reduces TNIK protein expression and the transcriptional activity of Wnt target genes, and promotes apoptosis in cancer cells, displaying anti-cancer properties. Furthermore, it functions as an ATP-competitive Traf2- and Nck-interacting kinase (TNIK) inhibitor with a Ki of 100 nM.
Molecular Weight:
352.41
Purity:
98.06%
CAS Number:
[1228280-29-2]
Formula:
C18H16N4O2S
Target:
MAPK|||Apoptosis|||Wnt/beta-catenin
T11793
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