L-745870 hydrochloride has excellent brain penetration. L-745870 hydrochloride is a high-affinity, selective and orally active human dopamine D4 receptor antagonist with a Ki of 0.43 nM, and considerably weaker D2 receptor affinity with a Ki of 960 nM and D3 receptor affinity with a Ki of 2300 nM.
Molecular Weight:
363.28
Purity:
97.36%
CAS Number:
[1173023-36-3]
Formula:
C18H20Cl2N4
Target:
Dopamine Receptor
T11799
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