L-NIO dihydrochloride, a potent and non-selective NADPH-dependent nitric oxide synthase (NOS) inhibitor, consistently induces focal ischemic infarct in rats. It exhibits inhibitory constants (Kis) of 1.7, 3.9, and 3.9 µM for neuronal (nNOS), endothelial (eNOS), and inducible (iNOS) forms, respectively.
Molecular Weight:
209.67
Purity:
99.99%
CAS Number:
[159190-44-0]
Formula:
C7H16ClN3O2
Target:
NOS|||NO Synthase
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