LS-102 is a selective inhibitor of the E3 ligase synoviolin (Syvn1), an astragaloside IV derivative, which attenuates myocardial ischemia/reperfusion injury by inhibiting mitochondrial fission.LS-102 inhibits Syvn1 auto-ubiquitylation, which ameliorates amyloidazole-induced slowing of the heart rate, and is useful for studying cardiovascular diseases.
Molecular Weight:
452.6
Purity:
98.92%
CAS Number:
[1456891-34-1]
Formula:
C24H36N8O
Target:
E1/E2/E3 Enzyme|||Ligand for E3 Ligase
T11879
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