LTbetaR-IN-1 is a potent and selective lymphin beta receptor (LTbetaR) inhibitor with a selective inhibitory effect on the nuclear translocation of p52 of TNF12A, without affecting the nuclear translocation of p65 mediated by the TNF-alpha receptor. It inhibits p52 nuclear translocation stimulated by TWEAK or Anti-LTbetaR with an IC50 of 10 µM and regulates the NF-kB signaling pathway in a ligand-independent manner.
Molecular Weight:
320.35
Purity:
99.09%
CAS Number:
[2189366-77-4]
Formula:
C18H16N4O2
Target:
LTR|||NF-kappaB
T11886
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