M8891 is an orally active, reversible, and brain-penetrant Methionine Aminopeptidase-2 (MetAP-2) inhibitor (IC50: 54 nM, Ki: 4.33 nM). It inhibits the growth of primary endothelial cells and tumor cells, demonstrating both antiangiogenic and antitumoral activity.
Molecular Weight:
385.36
CAS Number:
[1464842-09-8]
Formula:
C20H17F2N3O3
Target:
Others|||Aminopeptidase
T11930
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