MMAF-OMe (Monomethyl auristatin F methyl ester) is an antitubulin agent which inhibits several tumor cell lines with IC50s of 0.056 nM, 0.166 nM, 0.183 nM, and 0.449 nM for MDAMB435/5T4, MDAMB361DYT2, MDAMB468, and Raji (5T4-) cell lines, respectively. MMAF-Ome is also an ADC cytotoxin.
Molecular Weight:
745.99
Purity:
99.34%
CAS Number:
[863971-12-4]
Formula:
C40H67N5O8
Target:
ADC Cytotoxin
T12081
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