N-Desethyl Sunitinib (SU012662) is the primary active metabolite of Sunitinib produced by the metabolism of cytochrome P450 enzyme 3A4 (CYP3A4).Sunitinib is an orally available inhibitor of a number of tyrosine kinases involved in tumor proliferation and angiogenesis, including VEGFR, PDGFR, KIT, and FLT3, and was approved for the treatment of advanced/metastatic renal cell carcinoma (RCC)
Molecular Weight:
370.42
CAS Number:
[356068-97-8]
Formula:
C20H23FN4O2
Target:
c-Kit|||PDGFR|||Drug Metabolite|||FLT|||VEGFR
T12145
T12145
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