Palbociclib-d8 (PD 0332991 D8) is the 2H-labeled form of Palbociclib. Palbociclib is an orally active CDK inhibitor that inhibits CDK4 and CDK6 (IC50=11/16 nM). Palbociclib has anti-tumor activity and is used in research for estrogen receptor-positive and HER2-negative breast cancer.
Molecular Weight:
455.58
CAS Number:
[1628752-83-9]
Formula:
C24H21D8N7O2
Target:
CDK
T12355
T12355
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