SIAIS178, CAS [[2376047-73-1]]

Product Overview

• Article Name: SIAIS178, CAS [[2376047-73-1]]
• Biozol Catalog Number: TGM-T12907
• Supplier Catalog Number: T12907
• Alternative Catalog Number: TGM-T12907-1MLX10MM(INDMSO),TGM-T12907-1MG,TGM-T12907-5MG,TGM-T12907-10MG,TGM-T12907-25MG,TGM-T12907-50MG,TGM-T12907-100MG,TGM-T12907-200MG
• Manufacturer: TargetMol
• Category: Biochemikalien
• Alternative Names: SIAI S178

Product Description

SIAIS178 is a selective PROTAC degrader targeting BCR-ABL with an IC50 of 24 nM. It degrades BCR-ABL protein by recruiting the VHL E3 ubiquitin ligase, inhibiting leukaemia cell growth in vitro and causing regression of K562 xenograft tumours.

Product Properties

• Molecular Weight: 1012.68
• Purity: 98.07%
• CAS Number: [2376047-73-1]
• Formula: C50H62ClN11O6S2
• Target: PROTACs|||Ligands for E3 Ligase|||Bcr-Abl

Images

T12907

T12907