TCMDC-135051 is a potent and selective PfCLK3 protein kinase inhibitor demonstrating significant antiparasiticidal activity (EC50=320 nM) while exhibiting minimal off-target toxicity. It effectively hinders the transition from trophozoite to schizont, impairs transcription, and diminishes transmission to the mosquito vector.
Molecular Weight:
471.59
Purity:
98.21%
CAS Number:
[2413716-15-9]
Formula:
C29H33N3O3
Target:
Others|||Parasite
T13102
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