TD-428 is a highly specific degrader of BRD4(DC50 of 0.32 nM). TD-428 is a BET PROTAC, which comprises TD-106 (a CRBN ligand) linked to JQ1 (a BET inhibitor). TD-428 efficiently induce BET protein degradation.
Molecular Weight:
879.38
Formula:
C43H43ClN10O7S
Target:
Epigenetic Reader Domain|||PROTACs
T13105
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