5-Fluorouridine is a metabolite of 5-fluorouracil that inhibits rRNA synthesis in human colon cancer cells and exhibits antitumor and antiviral activity. 5-Fluorouridine exerts a cytotoxic effect on the growth of L1210 cells, with an IC50 value of 2 nM. 5-Fluorouridine binds to poly-A RNA and exhibits antiproliferative activity. 5-Fluorouridine can be used in studies of nucleic acid metabolism, cancer chemotherapy, and viral replication mechanisms.
Molecular Weight:
262.19
Purity:
99.53%
CAS Number:
[316-46-1]
Formula:
C9H11FN2O6
Target:
Apoptosis|||Drug Metabolite|||DNA/RNA Synthesis
T1349
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