AM679 is a potent and selective FLAP inhibitor with IC50 values of 2.2 nM (FLAP binding), 0.6 nM (hLA), and 154 nM (hWB). AM679 displays improved CYP inhibition characteristics, no CYP3A4 time-dependent inhibition or induction, and strong in vivo leukotriene inhibition in rodent BAL models after oral administration.
Molecular Weight:
692.87
Purity:
99.45%
CAS Number:
[1206880-66-1]
Formula:
C40H44N4O5S
Target:
FLAP|||LTR|||Cytochromes P450
T14205
T14205
* VAT and and shipping costs not included. Errors and price changes excepted
