BI8626 is a ubiquitin ligase HUWE1 inhibitor with protective effects against spontaneous desiccation syndrome in NOD/ShiLtj mice.BI8626 inhibits intracellular cholesterol and decreases the expression of phosphorylated ZAP-70, CD25, and other activation markers, and inhibits the proliferation of CD4 T-cells.
Molecular Weight:
440.54
Purity:
99.84%
CAS Number:
[1875036-75-1]
Formula:
C25H28N8
Target:
E1/E2/E3 Enzyme
T14569
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