BMS-509744 is a selective, ATP-competitive Itk inhibitor with an IC50 of 19 nM. It inhibits IL-8 expression and HIV infection, ameliorates pulmonary inflammation in allergic asthma mouse models, and reduces Imiquimod-induced skin inflammation in mice.
Molecular Weight:
623.83
Purity:
0.997
CAS Number:
[439575-02-7]
Formula:
C32H41N5O4S2
Target:
Others|||Tyrosine Kinases|||HIV Protease|||IL Receptor|||Immunology/Inflammation related
T14674
T14674
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