Bragsin2, CAS [[342795-08-8]]

Product Overview

• Article Name: Bragsin2, CAS [[342795-08-8]]
• Biozol Catalog Number: TGM-T14775
• Supplier Catalog Number: T14775
• Alternative Catalog Number: TGM-T14775-1MLX10MM(INDMSO),TGM-T14775-5MG,TGM-T14775-10MG,TGM-T14775-25MG,TGM-T14775-50MG,TGM-T14775-100MG
• Manufacturer: TargetMol
• Category: Biochemikalien
• Alternative Names: Bragsin 2 , 6-methoxy-5-nitro-2-(trifluoromethyl)chromen-4-one

Product Description

Bragsin2 (6-methoxy-5-nitro-2-(trifluoromethyl)chromen-4-one) is a hydration-resistant cell penetrant, selective and non-competitive inhibitor of Afr guanine nucleotide exchange factor BRAG2 that inhibits Arf GTPase activation, with an IC50 of 3 µM. Bragsin2 binds at the interface between the pleckstrin homology domain of BRAG2 and the lipid bilayer, leading BRAG2 unable to activate lipidated Arf GTPase.

Product Properties

• Molecular Weight: 289.16
• Purity: 99.87%
• CAS Number: [342795-08-8]
• Formula: C11H6F3NO5
• Target: MDM-2/p53|||Others|||Ras

Images

T14775