BRD6989 is an analog of the natural product cortistatin A (dCA). Which inhibits CDK8 and upregulates IL-10. BRD6989 inhibits the kinase activity of recombinant CDK8 or CDK19 complexes. BRD6989 selectively binds a complex of CDK8 with an IC50 of ~200 nM.
Molecular Weight:
264.33
Purity:
99.43%
CAS Number:
[642008-81-9]
Formula:
C16H16N4
Target:
Interleukin|||CDK|||IL Receptor
T14778
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