Carotegrast is a selective alpha4 integrin antagonist that inhibits the migration of inflammatory cells to the intestinal mucosa by blocking the interaction between alpha4beta1/alpha4beta7 integrins and their ligands. Carotegrast is used in research and clinical practice for the treatment of inflammatory bowel diseases such as ulcerative colitis, it exerts local anti-inflammatory effects and results in low systemic exposure.
Molecular Weight:
555.41
CAS Number:
[401904-75-4]
Formula:
C27H24Cl2N4O5
Target:
Integrin
T14876
T14876
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