CBS9106 (SL-801) is a reversible oral CRM1 inhibitor with CRM1 degrading and antitumor activity.CBS9106 inhibits CRM1-dependent nuclear export and reduces CRM1 protein levels.CBS9106 inhibits tumor growth and prolongs the survival of mice bearing tumor xenografts.CBS9106 is an inhibitor of CRM1-dependent nuclear export and reduces CRM1 protein levels.
Molecular Weight:
419.83
Purity:
98.98%
CAS Number:
[1076235-04-5]
Formula:
C18H21ClF3N3O3
Target:
CRM1|||Apoptosis
T14885
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