CDKI-73 is a potent CDK9 inhibitor (Ki: 4 nM). It shows selective toxicity to CLL cells(LD50=80 nM) versus normal B cell and normal CD34+ cell(LD50>20 uM).The inhibition of CDK9 induces apoptosis and potentiates the effect of cisplatin.
Molecular Weight:
394.45
Purity:
95.88%
CAS Number:
[1421693-22-2]
Formula:
C15H15FN6O2S2
Target:
Apoptosis|||CDK
T14919
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