Cenisertib is A potent ATP-competitive multi-kinase inhibitor, showing inhibitory effects on the activity of Aurora-kinase-A/B, ABL1, AKT, STAT5, FLT3, as well as kinase inhibitors of FER and its homolog. Cenisertib inhibits the growth of tumor mast cells (MCS) by inhibiting the activity of several different molecular targets. Cenisertib also inhibits tumor growth in pancreatic, breast, colon, ovarian and lung cancer and leukemia in xenograft models.
Molecular Weight:
451.54
CAS Number:
[871357-89-0]
Formula:
C24H30FN7O
Target:
STAT|||Aurora Kinase|||Akt|||FLT|||Bcr-Abl
T14925
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