CMS-121, a quinolone derivative, is an orally active acetyl-CoA carboxylase 1 (ACC1) inhibitor. CMS-121 protects HT22 cells against ischemia and oxidative damage (EC50: 7 nM and 200 nM). CMS-121 shows strong neuroprotective, antioxidative, anti-inflammatory, and renoprotective activities.
Molecular Weight:
321.37
Purity:
98.71%
CAS Number:
[1353224-53-9]
Formula:
C20H19NO3
Target:
Acetyl-CoA Carboxylase
T14991
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