D5D-IN-326 is an orally active delta-5 desaturase (D5D) inhibitor (IC50s: 72 and 22 nM for rat and human D5D in enzymic and cell-based assays). It has no effect on D6D or D9D activity. D5D-IN-326 reduces insulin resistance and decreases body weight in diet-induced obese C57BL/6J mice.
Molecular Weight:
473.27
CAS Number:
[1236767-85-3]
Formula:
C17H11F8N3O4
Target:
Others|||Stearoyl-CoA Desaturase (SCD)
T15043
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