Flindokalner (BMS-204352) is a potassium channel modulator and a positive modulator of all neuronal Kv7 channel subtypes expressed in HEK293 cells. It is also a positive modulator of large conductance calcium-activated K channels (BKca) and displays negative modulatory activity at Kv7.1 channels (Ki = 3.7 µM). Additionally, Flindokalner acts as a negative modulator of GABAA receptors and demonstrates anxiolytic efficacy in vivo.
Molecular Weight:
359.7
Purity:
99.25%
CAS Number:
[187523-35-9]
Formula:
C16H10ClF4NO2
Target:
Potassium Channel
T15286
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