Fluorofenidone (AKF-PD) attenuates the progression of renal interstitial fibrosis partly by suppressing NADPH oxidase and extracellular matrix (ECM) deposition via the PI3K/Akt signalling pathway. Fluorofenidone is an analogue of AMR69. Which displays equivalent lower toxicity, antifibrotic activity, and longer half-life.
Molecular Weight:
203.21
Purity:
99.85%
CAS Number:
[848353-85-5]
Formula:
C12H10FNO
Target:
Akt|||PI3K|||Others
T15300
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