Cisplatin (CDDP) is a chemotherapeutic agent with antitumor activity and is a classic DNA crosslinker. It inhibits DNA synthesis and induces DNA damage in cancer cells by forming DNA adducts, ultimately leading to cell death. In addition, Cisplatin can activate ferroptosis and induce autophagy. In animal studies, it is commonly used to establish models of chronic kidney injury and acute renal failure.
Molecular Weight:
300.04
Purity:
97.13%
CAS Number:
[15663-27-1]
Formula:
Cl2H6N2Pt
Target:
DNA Alkylator/Crosslinker|||DNA/RNA Synthesis|||Ferroptosis|||Autophagy
T1564
T1564
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