CLZ-8 (Mcl1-IN-8) is an orally active inhibitor of Mcl-1-PUMA (p53 up-regulated mediator of apoptosis) with radioprotective properties.CLZ-8 ameliorates radiation-induced HUVEC cell damage and reduces apoptosis counts, and inhibits radiation-induced overexpression of PUMA.
Molecular Weight:
393.5
Purity:
99.85%
CAS Number:
[678158-55-9]
Formula:
C22H23N3O2S
Target:
Bcl-2 Family|||Apoptosis
T16030
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